His family announced that Prince Frederik of Luxembourg died of 22-year-old Polg mitochondria disease, a rare genetic disease he was born.
Prince Robert of Luxembourg held the second day of the internationally recognized rare sickness day on the last day of February, and Frederik de Nassau died in Paris on March 1. Prince Frederik formed the organization in 2021 to help raise awareness about the situation.
Courtesy: polgfoundation.org
Prince Robert; his wife Princess Julie, Princess Nassau; the patriarch said that Prince Frederick’s siblings Alexander and Charlotte were able to say goodbye to him on his last day. The last thing Frederik asked him was: “Dad, are you proud of me?” According to Prince Robert.
“He couldn’t speak for days or days, so the clarity of these words is as surprising as the weight of the moment,” Prince Robert wrote. “The answer is very easy, and he heard it many times…but, for now, he needs to be so relieved that he has contributed everything possible to his short and beautiful survival, and now he can finally move on.”
The young prince is remembered as a happy man with a “tenacious desire.” Prince Robert said he is learning Italian and a big fan of the American adaptation of the Office, and he has seen it more than 10 times.
What is POLG mitochondrial disease?
According to the National Library of Medicine, Polg is the name of a gene that provides a directive to make an active work of a protein called polymerase gamma, called the Alpha subunit.
There are a variety of POLG-related diseases and diseases, including Alpers-Huttenlocher syndrome, ataxia neuropathy spectrum, and myocerebral myocerebral disease spectrum in childhood.
Frederik was born in Polg, but he was not diagnosed until he was 14 years old.
According to the POLG Foundation, the mitochondrial disease Frederik “robbed the body’s energy cells” and could cause a variety of symptoms, including progressive dysfunction and failure of multiple organs.
“People may compare it to a faulty battery that has never been fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully fully
Experts estimate that about 2% of the population has POLG mutations. However, the total number of people with POLG-related diseases is not known. A study of POLG mutations used in Australian adults found that 10% of them had POLG-related diseases.
